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The high-speed rail collision in southern Spain happened Sunday when the tail end of a train jumped the track, causing another train to derail. The official death toll rose to 41 by Tuesday morning.

Warming temperatures are forcing Antarctic penguins to breed earlier and that's a big problem for two of the cute tuxedoed species that face extinction by the end of the century, a study said.

It's unclear how many leaders have been asked to join the board, and the large number of invitations being sent out, including to countries that don't get along, has raised questions about the board's mandate and decision-making processes.

Indiana bullied its way into the history books Monday night, toppling Miami 27-21 to put the finishing touch on a rags-to-riches story, an undefeated season and the national title.

Medicaid is doing a novel payment system for the new, promising and expensive sickle cell treatment. It may become a model for all gene therapies being developed.